Xin‐Jie Chu

Discovery of RG7388, a Potent and Selective p53–MDM2 Inhibitor in Clinical Development

Qingjie Ding, Zhuming Zhang, Jinjun Liu et al. · Journal of Medicinal Chemistry · 2013 · 583 citations · Full text

Drug Target, Chemical Biology, Cancer Biology +19

Total Synthesis of Vancomycin—Part 1: Design and Development of Methodology

K. C. Nicolaou, Hui Li, Christopher N. Boddy et al. · Chemistry - A European Journal · 1999 · 157 citations

Glycobiology, Organic Chemistry, Peptide Science +16

Discovery of [4-Amino-2-(1-methanesulfonylpiperidin-4-ylamino)pyrimidin-5-yl](2,3-difluoro-6- methoxyphenyl)methanone (R547), A Potent and Selective Cyclin-Dependent Kinase Inhibitor with Significant in Vivo Antitumor Activity

Xin‐Jie Chu, Wanda DePinto, David Bartkovitz et al. · Journal of Medicinal Chemistry · 2006 · 116 citations · Full text

Drug Target, Pharmacotherapy, Cell Cycle +17

<i>In vitro</i> and <i>in vivo</i> activity of R547: a potent and selective cyclin-dependent kinase inhibitor currently in phase I clinical trials

Wanda DePinto, Xin‐Jie Chu, Xuefeng Yin et al. · Molecular Cancer Therapeutics · 2006 · 102 citations · Full text

Molecular Pharmacology, Tumor Biology, Cell Cycle Block +15

Total Synthesis of Brevetoxin A: Part 1: First Generation Strategy and Construction of BCD Ring System

K. C. Nicolaou, Mark E. Bunnage, Daniel McGarry et al. · Chemistry - A European Journal · 1999 · 90 citations

Biosynthesis, Bioorganic Chemistry, Part 1 +13