Andreas Tosstorff

Advancing Therapeutic Protein Discovery and Development through Comprehensive Computational and Biophysical Characterization

Lorenzo Gentiluomo, Hristo L. Svilenov, Dillen Augustijn et al. · Molecular Pharmaceutics · 2019 · 48 citations · Full text

Life Sciences, Biochemistry, Pharmaceutical Analysis +14

A high quality, industrial data set for binding affinity prediction: performance comparison in different early drug discovery scenarios

Andreas Tosstorff, M.G. Rudolph, Jason C. Cole et al. · Journal of Computer-Aided Molecular Design · 2022 · 31 citations · Full text

Pharmacy, Bioinformatics, Medicinal Chemistry +17

Mediated electron transfer with monooxygenases—Insight in interactions between reduced mediators and the co-substrate oxygen

Andreas Tosstorff, Alexander Dennig, Anna Joëlle Ruff et al. · Journal of Molecular Catalysis B Enzymatic · 2014 · 25 citations

Life Sciences, Biochemistry, Molecular Biology +14

Discovery of Orally Available and Brain Penetrant AEP Inhibitors

Daniela Krummenacher, Weiping He, Bernd Kuhn et al. · Journal of Medicinal Chemistry · 2023 · 16 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Structure-based discovery of a new protein-aggregation breaking excipient

Andreas Tosstorff, Hristo L. Svilenov, Günther H. Peters et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2019 · 15 citations · Full text

Life Sciences, Biochemistry, Drug Design +13