Nicholas P. Ho

Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for μ-Opioid Receptor and Opioid-Like Behavioral Effects in Rats

Samuel Obeng, Jenny L. Wilkerson, Francisco León et al. · Journal of Pharmacology and Experimental Therapeutics · 2020 · 102 citations · Full text

Medicine, Pharmacology, Molecular Pharmacology +14

Interactive Effects of µ-Opioid and Adrenergic-α2 Receptor Agonists in Rats: Pharmacological Investigation of the Primary Kratom Alkaloid Mitragynine and Its Metabolite 7-Hydroxymitragynine

Samuel Obeng, Francisco León, Avi Patel et al. · Journal of Pharmacology and Experimental Therapeutics · 2022 · 42 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

The Lack of Contribution of 7-Hydroxymitragynine to the Antinociceptive Effects of Mitragynine in Mice: A Pharmacokinetic and Pharmacodynamic Study

Erin C. Berthold, Shyam H. Kamble, Raju S. Kanumuri et al. · Drug Metabolism and Disposition · 2021 · 30 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

The Mitragyna speciosa (kratom) alkaloid mitragynine: Analysis of adrenergic α2 receptor activity in vitro and in vivo

Samuel Obeng, Morgan L. Crowley, Marco Mottinelli et al. · European Journal of Pharmacology · 2024 · 19 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9

Ventilatory Effects of Fentanyl, Heroin, and d-Methamphetamine, Alone and in Mixtures in Male Rats Breathing Normal Air

Takato Hiranita, Nicholas P. Ho, Charles P. France · Journal of Pharmacology and Experimental Therapeutics · 2023 · 17 citations · Full text

Pharmacy, Pharmacology, Toxicology +13