Marco Mottinelli

Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for μ-Opioid Receptor and Opioid-Like Behavioral Effects in Rats

Samuel Obeng, Jenny L. Wilkerson, Francisco León et al. · Journal of Pharmacology and Experimental Therapeutics · 2020 · 96 citations · Full text

Activity of <i>Mitragyna speciosa</i> (“Kratom”) Alkaloids at Serotonin Receptors

Francisco León, Samuel Obeng, Marco Mottinelli et al. · Journal of Medicinal Chemistry · 2021 · 71 citations · Full text

Directed Biosynthesis of Mitragynine Stereoisomers

Carsten Schotte, Yindi Jiang, Dagny Grzech et al. · Journal of the American Chemical Society · 2023 · 56 citations · Full text

Efficient preparation of an N-aryl β-amino acid via asymmetric hydrogenation and direct asymmetric reductive amination en route to Ezetimibe

Guuske F. Busscher, Laurent Lefort, Jozef G.O. Cremers et al. · Tetrahedron Asymmetry · 2010 · 41 citations · Full text

Engineering, Biochemistry, N-aryl β-Amino Acid +7

Characterization of Sigma 1 Receptor Antagonist CM-304 and Its Analog, AZ-66: Novel Therapeutics Against Allodynia and Induced Pain

Thomas J. Cirino, Shainnel O. Eans, Jéssica Medina et al. · Frontiers in Pharmacology · 2019 · 40 citations · Full text