Guuske F. Busscher

Elongated Multiple Electronic Cascade and Cyclization Spacer Systems in Activatible Anticancer Prodrugs for Enhanced Drug Release

Franciscus M. H. de Groot, Walter J. Loos, Ralph Koekkoek et al. · The Journal of Organic Chemistry · 2001 · 117 citations

Combinatorial Chemistry, Novel Spacer Systems, Cyclization Spacer Systems +16

Novel 20-Carbonate Linked Prodrugs of Camptothecin and 9-Aminocamptothecin Designed for Activation by Tumour-Associated Plasmin

Franciscus M. H. de Groot, Guuske F. Busscher, R. W. M. ABEN et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 48 citations

Medicinal Chemistry, Biochemistry, Natural Sciences +9

Efficient preparation of an N-aryl β-amino acid via asymmetric hydrogenation and direct asymmetric reductive amination en route to Ezetimibe

Guuske F. Busscher, Laurent Lefort, Jozef G.O. Cremers et al. · Tetrahedron Asymmetry · 2010 · 41 citations · Full text

Engineering, Biochemistry, N-aryl β-Amino Acid +7

Efficient Preparation of a 1,3-Diazidocyclitol as a Versatile 2-Deoxystreptamine Precursor

Guuske F. Busscher, Stan Groothuys, R. De Gelder et al. · The Journal of Organic Chemistry · 2004 · 26 citations

Synthesis of a protected enantiomerically pure 2-deoxystreptamine derivative from d-allylglycine

Guuske F. Busscher, Floris P. J. T. Rutjes, Floris L. van Delft · Tetrahedron Letters · 2004 · 24 citations · Full text

Bioorganic Chemistry, Natural Sciences, Medicine +9