Shyam H. Kamble

Investigation of the Adrenergic and Opioid Binding Affinities, Metabolic Stability, Plasma Protein Binding Properties, and Functional Effects of Selected Indole-Based Kratom Alkaloids

Samuel Obeng, Shyam H. Kamble, Morgan E. Reeves et al. · Journal of Medicinal Chemistry · 2019 · 158 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Simultaneous quantification of ten key Kratom alkaloids in <i>Mitragyna speciosa</i> leaf extracts and commercial products by ultra‐performance liquid chromatography−tandem mass spectrometry

Abhisheak Sharma, Shyam H. Kamble, Francisco León et al. · Drug Testing and Analysis · 2019 · 109 citations · Full text

Pharmacy, Pharmaceutical Analysis, Pharmacology +16

Metabolite profiling and identification of enzymes responsible for the metabolism of mitragynine, the major alkaloid of <i>Mitragyna speciosa</i> (kratom)

Shyam H. Kamble, Abhisheak Sharma, Tamara I. King et al. · Xenobiotica · 2018 · 94 citations

Medicine, Medicinal Chemistry, Pharmacology +16

Activity of <i>Mitragyna speciosa</i> (“Kratom”) Alkaloids at Serotonin Receptors

Francisco León, Samuel Obeng, Marco Mottinelli et al. · Journal of Medicinal Chemistry · 2021 · 83 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Exploration of cytochrome P450 inhibition mediated drug-drug interaction potential of kratom alkaloids

Shyam H. Kamble, Abhisheak Sharma, Tamara I. King et al. · Toxicology Letters · 2019 · 77 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16