Lorena Galán-Acosta

Degradation of HK2 by chaperone-mediated autophagy promotes metabolic catastrophe and cell death

Hongguang Xia, Ayaz Najafov, Jiefei Geng et al. · The Journal of Cell Biology · 2015 · 121 citations · Full text

Intravenous treatment with a molecular chaperone designed against β-amyloid toxicity improves Alzheimer’s disease pathology in mouse models

Shaffi Manchanda, Lorena Galán-Acosta, Axel Abelein et al. · Molecular Therapy · 2022 · 33 citations · Full text

β-Amyloid Toxicity, Neurochemical Biomarkers, Aβ42 Oligomer Generation +20

Recombinant BRICHOS chaperone domains delivered to mouse brain parenchyma by focused ultrasound and microbubbles are internalized by hippocampal and cortical neurons

Lorena Galán-Acosta, Carlos Sierra, Axel Leppert et al. · Molecular and Cellular Neuroscience · 2020 · 22 citations · Full text

Brichos Domains, Cellular Neurobiology, Social Sciences +18

Blood–brain and blood–cerebrospinal fluid passage of BRICHOS domains from two molecular chaperones in mice

Simone Tambaro, Lorena Galán-Acosta, Axel Leppert et al. · Journal of Biological Chemistry · 2019 · 21 citations · Full text

Amyloid-β Peptide Targeting Peptidomimetics for Prevention of Neurotoxicity

Dmytro Honcharenko, Alok Juneja, Firoz Roshan et al. · ACS Chemical Neuroscience · 2019 · 14 citations