Aristeidis E. Boukouris

Inhibition of pyruvate dehydrogenase kinase improves pulmonary arterial hypertension in genetically susceptible patients

Evangelos D. Michelakis, Vikram Gurtu, Linda Webster et al. · Science Translational Medicine · 2017 · 311 citations

Medicine, Cardiology, Pharmacology +7

The Degree of Liver Injury Determines the Role of P21 in Liver Regeneration And Hepatocarcinogenesis in Mice

Laura Elisa Buitrago‐Molina, Silke Marhenke, Thomas Longerich et al. · Hepatology · 2013 · 92 citations · Full text

Medicine, Molecular Biology, Oncology +17

Tissue-specific regulation of p53 by PKM2 is redox dependent and provides a therapeutic target for anthracycline-induced cardiotoxicity

Bruno Saleme, Vikram Gurtu, Yongneng Zhang et al. · Science Translational Medicine · 2019 · 88 citations

Medicine, Oncology, Pharmacology +15

MFN2-driven mitochondria-to-nucleus tethering allows a non-canonical nuclear entry pathway of the mitochondrial pyruvate dehydrogenase complex

Sotirios Zervopoulos, Aristeidis E. Boukouris, Bruno Saleme et al. · Molecular Cell · 2022 · 68 citations

Life Sciences, Cell Biology, Molecular Biology +10

Activity of the <scp>mTOR</scp> inhibitor RAD001, the dual <scp>mTOR</scp> and PI3‐kinase inhibitor BEZ235 and the PI3‐kinase inhibitor BKM120 in hepatocellular carcinoma

Martha M. Kirstein, Aristeidis E. Boukouris, Deepika Pothiraju et al. · Liver International · 2013 · 43 citations

Medicine, Oncology, Pharmacology +17