Evangelos D. Michelakis

A Mitochondria-K+ Channel Axis Is Suppressed in Cancer and Its Normalization Promotes Apoptosis and Inhibits Cancer Growth

Sébastien Bonnet, Stephen L. Archer, Joan Allalunis‐Turner et al. · Cancer Cell · 2007 · 1.5K citations · Full text

Life Sciences, Cancer Biology, Oncology +14

Metabolic Modulation of Glioblastoma with Dichloroacetate

Evangelos D. Michelakis, Gopinath Sutendra, Peter Dromparis et al. · Science Translational Medicine · 2010 · 715 citations

Life Sciences, Biochemistry, Oncology +17

A Nuclear Pyruvate Dehydrogenase Complex Is Important for the Generation of Acetyl-CoA and Histone Acetylation

Gopinath Sutendra, Adam Kinnaird, Peter Dromparis et al. · Cell · 2014 · 652 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +7

An Abnormal Mitochondrial–Hypoxia Inducible Factor-1α–Kv Channel Pathway Disrupts Oxygen Sensing and Triggers Pulmonary Arterial Hypertension in Fawn Hooded Rats

Sébastien Bonnet, Evangelos D. Michelakis, Christopher J. Porter et al. · Circulation · 2006 · 583 citations

Life Sciences, Cardiology, Physiology +17

Oral Sildenafil Is an Effective and Specific Pulmonary Vasodilator in Patients With Pulmonary Arterial Hypertension

Evangelos D. Michelakis, Wayne Tymchak, Dale Lien et al. · Circulation · 2002 · 578 citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +15