Alex J. Bott

The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure

Ahmad A. Cluntun, Rachit Badolia, Sandra Lettlová et al. · Cell Metabolism · 2020 · 305 citations · Full text

Cardiac Muscle, Cardiomyopathy, Heart Failure +6

Oncogenic Myc Induces Expression of Glutamine Synthetase through Promoter Demethylation

Alex J. Bott, I‐Chen Peng, Yongjun Fan et al. · Cell Metabolism · 2015 · 254 citations · Full text

Protein Expression, Natural Sciences, Protein Biosynthesis +8

TRIM21 Ubiquitylates SQSTM1/p62 and Suppresses Protein Sequestration to Regulate Redox Homeostasis

Ji-An Pan, Yu Sun, Ya-Ping Jiang et al. · Molecular Cell · 2016 · 253 citations · Full text

Redox Signaling, Redox Regulator, Genetics +8

Glutamine Anabolism Plays a Critical Role in Pancreatic Cancer by Coupling Carbon and Nitrogen Metabolism

Alex J. Bott, Jianliang Shen, Claudia Tonelli et al. · Cell Reports · 2019 · 185 citations · Full text

Regulation of Tumor Initiation by the Mitochondrial Pyruvate Carrier

Claire Bensard, Dona R. Wisidagama, Kristofor A. Olson et al. · Cell Metabolism · 2019 · 171 citations · Full text

Mitochondrial Biogenesis, Mitochondrial Function, Biochemistry +5