Oncogenic Myc Induces Expression of Glutamine Synthetase through Promoter Demethylation

Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine

Shinsuke Ito, Li Shen, Qing Dai et al. · Science · 2011 · 3.3K citations

Chromatin, Developmental Biology, Natural Sciences +15

Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA

Yufei He, Bin-Zhong Li, Zheng Li et al. · Science · 2011 · 2.7K citations

Epigenetic Change, Dna Methylation, Molecular Biology +19

Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

Ralph J. DeBerardinis, Anthony Mancuso, Evgueni Daikhin et al. · Proceedings of the National Academy of Sciences · 2007 · 2.5K citations · Full text

Metabolic Remodeling, Cellular Physiology, Protein Synthesis +21

Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse

Sunil R. Hingorani, Emanuel F. Petricoin, Anirban Maitra et al. · Cancer Cell · 2003 · 2.5K citations · Full text

Tumor Biology, Pancreatic Cancer, Medicine +8

c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

Ping Gao, Irina Tchernyshyov, Tsung-Cheng Chang et al. · Nature · 2009 · 2.1K citations · Full text

Glutamine Metabolism, Mitochondrial Function, Mitochondrial Dynamic +8