Alyssa Sproles

CD4 <b>+</b> CD25 <b>+</b> T cells protect against experimentally induced asthma and alter pulmonary dendritic cell phenotype and function

Ian Lewkowich, Nancy Herman, Kathleen W. Schleifer et al. · The Journal of Experimental Medicine · 2005 · 392 citations · Full text

Complement-mediated regulation of the IL-17A axis is a central genetic determinant of the severity of experimental allergic asthma

Stéphane Lajoie, Ian Lewkowich, Yusuke Suzuki et al. · Nature Immunology · 2010 · 328 citations · Full text

Inflammation, Asthma, Immunogenetics +11

Partial restoration of T‐cell function in aged mice by <i>in vitro</i> blockade of the PD‐1/ PD‐L1 pathway

Celine S. Lages, Ian Lewkowich, Alyssa Sproles et al. · Aging Cell · 2010 · 147 citations · Full text

Adaptive Immune System, T-regulatory Cell, Immunology +19

Allergen Uptake, Activation, and IL-23 Production by Pulmonary Myeloid DCs Drives Airway Hyperresponsiveness in Asthma-Susceptible Mice

Ian Lewkowich, Stéphane Lajoie, Jennifer Clark et al. · PLoS ONE · 2008 · 98 citations · Full text

Asthma, Inflammatory Lung Disease, Lung Inflammation +18

Differential control of CD4⁺ T‐cell subsets by the PD‐1/PD‐L1 axis in a mouse model of allergic asthma

Jaclyn W. McAlees, Stéphane Lajoie, Krista Dienger et al. · European Journal of Immunology · 2015 · 77 citations · Full text

Asthma, Inflammatory Lung Disease, Adaptive Immune System +20