Amandine Boller

Substituted pyrrolidin-2-ones: Centrally acting orexin receptor antagonists promoting sleep. Part 2

Thierry Sifferlen, Amandine Boller, Audrey Chardonneau et al. · Bioorganic & Medicinal Chemistry Letters · 2015 · 33 citations · Full text

Sleep Disorders, Sleep, Sleep Medicine +9

Discovery of substituted lactams as novel dual orexin receptor antagonists. Synthesis, preliminary structure–activity relationship studies and efforts towards improved metabolic stability and pharmacokinetic properties. Part 1

Thierry Sifferlen, Amandine Boller, Audrey Chardonneau et al. · Bioorganic & Medicinal Chemistry Letters · 2014 · 17 citations · Full text

Pharmacokinetic Properties, Molecular Pharmacology, Pharmaceutical Science +10

Structure–activity relationship studies and sleep-promoting activity of novel 1-chloro-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine derivatives as dual orexin receptor antagonists. Part 2

Thierry Sifferlen, Ralf Koberstein, Emmanuelle Cottreel et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 13 citations · Full text

Biochemistry, Medicine, Mechanism Of Action +7

Synthesis, structure–activity relationship studies, and identification of novel 5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine derivatives as dual orexin receptor antagonists. Part 1

Thierry Sifferlen, Ralf Koberstein, Emmanuelle Cottreel et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 12 citations · Full text

Molecular Pharmacology, Biochemistry, Medicine +9