Sophie Roerink

Tissue-specific mutation accumulation in human adult stem cells during life

Francis Blokzijl, Joep de Ligt, Myrthe Jager et al. · Nature · 2016 · 960 citations · Full text

Embryonic Stem Cell, Developmental Biology, Medicine +9

Intra-tumour diversification in colorectal cancer at the single-cell level

Sophie Roerink, Nobuo Sasaki, Henry Lee-Six et al. · Nature · 2018 · 554 citations

Tumor Biology, Tumor Heterogeneity, Medicine +5

Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells

Juan I. Garaycoechea, Gerry P. Crossan, Frédéric Langevin et al. · Nature · 2018 · 398 citations · Full text

Chromatin, Genome Instability, Dna Damage +9

Genome sequencing of normal cells reveals developmental lineages and mutational processes

Sam Behjati, Meritxell Huch, Ruben van Boxtel et al. · Nature · 2014 · 367 citations

Cell Lineage, Sequencing, Developmental Biology +12

Polymerase theta-mediated end joining of replication-associated DNA breaks in <i>C. elegans</i>

Sophie Roerink, Robin van Schendel, Marcel Tijsterman · Genome Research · 2014 · 164 citations · Full text

Rna Processing, Genome Instability, Collapsed Replication +15