Pei-Ling Chen

Loss of PTEN Promotes Resistance to T Cell–Mediated Immunotherapy

Weiyi Peng, Jie Qing Chen, Chengwen Liu et al. · Cancer Discovery · 2015 · 1.5K citations · Full text

Medicine, Immunology, Oncology +17

Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy

Jianjun Gao, Lewis Z. Shi, Hao Zhao et al. · Cell · 2016 · 1.3K citations · Full text

Medicine, Immunology, Oncology +16

Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade

Pei-Ling Chen, Whijae Roh, Alexandre Reuben et al. · Cancer Discovery · 2016 · 1K citations · Full text

Life Sciences, Immunology, Oncology +17

Systematic identification of signaling pathways with potential to confer anticancer drug resistance

Colin A. Martz, Kathleen Ottina, Katherine R. Singleton et al. · Science Signaling · 2014 · 199 citations

Medicine, Oncology, Pharmacology +17

Genomic and immune heterogeneity are associated with differential responses to therapy in melanoma

Alexandre Reuben, Christine N. Spencer, Peter A. Prieto et al. · npj Genomic Medicine · 2017 · 189 citations · Full text

Medicine, Immunology, Oncology +17