Christine N. Spencer

Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade

Pei-Ling Chen, Whijae Roh, Alexandre Reuben et al. · Cancer Discovery · 2016 · 1K citations · Full text

Life Sciences, Immunology, Oncology +17

Integrated molecular analysis of tumor biopsies on sequential CTLA-4 and PD-1 blockade reveals markers of response and resistance

Whijae Roh, Alexandre Reuben, Christine N. Spencer et al. · Science Translational Medicine · 2017 · 920 citations · Full text

Medicine, Immunology, Oncology +17

T cell immunotherapies engage neutrophils to eliminate tumor antigen escape variants

Daniel Hirschhorn, Sadna Budhu, Lukas Kraehenbuehl et al. · Cell · 2023 · 296 citations · Full text

Life Sciences, Cancer Biology, Immunology +14

Cell culture model that mimics drusen formation and triggers complement activation associated with age-related macular degeneration

Lincoln V. Johnson, David L. Forest, Christopher D. Banna et al. · Proceedings of the National Academy of Sciences · 2011 · 201 citations · Full text

Medicine, Cell Biology, Ophthalmology +17

Genomic and immune heterogeneity are associated with differential responses to therapy in melanoma

Alexandre Reuben, Christine N. Spencer, Peter A. Prieto et al. · npj Genomic Medicine · 2017 · 189 citations · Full text

Medicine, Immunology, Oncology +17