Joseph G. Neduvelil

HOLE: A program for the analysis of the pore dimensions of ion channel structural models

Oliver S. Smart, Joseph G. Neduvelil, Xiaonan Wang et al. · Journal of Molecular Graphics · 1996 · 1.9K citations

Natural Sciences, Biophysics, Crystal Structure +13

Photoactivated γ-secretase inhibitors directed to the active site covalently label presenilin 1

Yue‐Ming Li, Min Xu, Ming‐Tain Lai et al. · Nature · 2000 · 869 citations

Life Sciences, Biochemistry, Molecular Biology +14

2-Aryl tryptamines: selective high-affinity antagonists for the h5-HT2A receptor

Graeme I. Stevenson, Adrian L. Smith, Stephen J. Lewis et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 84 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

A novel series of potent γ-secretase inhibitors based on a benzobicyclo[4.2.1]nonane core

Stephen J. Lewis, Adrian L. Smith, Joseph G. Neduvelil et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 46 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +6

γ-Secretase: characterization and implication for Alzheimer disease therapy

Min Xu, Ming‐Tain Lai, Qian Huang et al. · Neurobiology of Aging · 2002 · 34 citations

Life Sciences, Biochemistry, Neuroscience +12