Joseph G. Neduvelil

HOLE: A program for the analysis of the pore dimensions of ion channel structural models

Oliver S. Smart, Joseph G. Neduvelil, Xiaonan Wang et al. · Journal of Molecular Graphics · 1996 · 1.9K citations

Pore Structure, Physics, Natural Sciences +11

Photoactivated γ-secretase inhibitors directed to the active site covalently label presenilin 1

Yue‐Ming Li, Min Xu, Ming‐Tain Lai et al. · Nature · 2000 · 864 citations

Molecular Pharmacology, Medicinal Chemistry, Protein Secretion +12

2-Aryl tryptamines: selective high-affinity antagonists for the h5-HT2A receptor

Graeme I. Stevenson, Adrian L. Smith, Stephen J. Lewis et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 84 citations · Full text

Biochemistry, Functional Selectivity, Medicine +6

A novel series of potent γ-secretase inhibitors based on a benzobicyclo[4.2.1]nonane core

Stephen J. Lewis, Adrian L. Smith, Joseph G. Neduvelil et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 46 citations · Full text

Medicinal Chemistry, Potent γ-Secretase Inhibitors, Novel Series +11

γ-Secretase: characterization and implication for Alzheimer disease therapy

Min Xu, Ming‐Tain Lai, Qian Huang et al. · Neurobiology of Aging · 2002 · 34 citations

Neurodegenerative Diseases, Alzheimer's Disease, Alzheimer Disease Therapy +7