Qian Huang

Photoactivated γ-secretase inhibitors directed to the active site covalently label presenilin 1

Yue‐Ming Li, Min Xu, Ming‐Tain Lai et al. · Nature · 2000 · 864 citations

Molecular Pharmacology, Medicinal Chemistry, Protein Secretion +12

Genome-Scale RNAi Screen for Host Factors Required for HIV Replication

Honglin Zhou, Min Xu, Qian Huang et al. · Cell Host & Microbe · 2008 · 773 citations · Full text

Viral Replication, Host Factor, Natural Sciences +9

Presenilin 1 is linked with γ-secretase activity in the detergent solubilized state

Yue‐Ming Li, Ming‐Tain Lai, Min Xu et al. · Proceedings of the National Academy of Sciences · 2000 · 534 citations · Full text

Protein Secretion, Molecular Biology, Amyloid Precursor Protein +17

Discovery of MK‐8742: An HCV NS5A Inhibitor with Broad Genotype Activity

Craig A. Coburn, Peter T. Meinke, Wei Chang et al. · ChemMedChem · 2013 · 196 citations · Full text

Hcv Ns5a Inhibitor, Broad Genotype Activity, Vitro Potency Profiles +17

Presenilin-1 and Presenilin-2 Exhibit Distinct yet Overlapping γ-Secretase Activities

Ming‐Tain Lai, Elizabeth Chen, Ming‐Chih Crouthamel et al. · Journal of Biological Chemistry · 2003 · 168 citations · Full text