Alex Agelidis

The ubiquitin-modifying enzyme A20 restricts ubiquitination of the kinase RIPK3 and protects cells from necroptosis

Michio Onizawa, Shigeru Oshima, Ulf Schulze‐Topphoff et al. · Nature Immunology · 2015 · 273 citations · Full text

Ubiquitin-modifying Enzyme A20, Kinase Ripk3, Signal Transduction +10

Dimerization and Ubiquitin Mediated Recruitment of A20, a Complex Deubiquitinating Enzyme

Timothy T. Lu, Michio Onizawa, Gianna Hammer et al. · Immunity · 2013 · 210 citations · Full text

Complex Deubiquitinating Enzyme, Protein Function, Biochemistry +5

Cell Entry Mechanisms of HSV: What we have Learned in Recent Years

Alex Agelidis, Deepak Shukla · Future Virology · 2015 · 191 citations · Full text

Viral Replication, Viral Pathogenesis, Immunology +17

Heparanase is a host enzyme required for herpes simplex virus-1 release from cells

Satvik Hadigal, Alex Agelidis, Ghadah A. Karasneh et al. · Nature Communications · 2015 · 138 citations · Full text

Viral Activation of Heparanase Drives Pathogenesis of Herpes Simplex Virus-1

Alex Agelidis, Satvik Hadigal, Dinesh Jaishankar et al. · Cell Reports · 2017 · 88 citations · Full text

Viral Replication, Molecular Virology, Pathogenesis +12