J. Nathaniel Diehl

Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer

Kirsten L. Bryant, Clint A. Stalnecker, Daniel Zeitouni et al. · Nature Medicine · 2019 · 695 citations

Tumor Biology, Cell Autophagy, Pancreatic Cancer +9

Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer

G. Aaron Hobbs, Nicole M. Baker, Anne M. Miermont et al. · Cancer Discovery · 2019 · 210 citations · Full text

Gain-of-Function <i>RHOA</i> Mutations Promote Focal Adhesion Kinase Activation and Dependency in Diffuse Gastric Cancer

Haisheng Zhang, Antje Schaefer, Yichen Wang et al. · Cancer Discovery · 2019 · 165 citations · Full text

Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers

Irem Ozkan‐Dagliyan, J. Nathaniel Diehl, Samuel D. George et al. · Cell Reports · 2020 · 97 citations · Full text

Kras Mutant Cancers, Apoptosis, Cell Death +19

Overall survival in a trial of orally administered CCR2 inhibitor CCX872 in locally advanced/metastatic pancreatic cancer: Correlation with blood monocyte counts.

David C. Linehan, Marcus Smith Noel, Aram F. Hezel et al. · Journal of Clinical Oncology · 2018 · 90 citations

Immunology, Pathology, Immunotherapeutics +19