Kirsten L. Bryant

Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer

Kirsten L. Bryant, Clint A. Stalnecker, Daniel Zeitouni et al. · Nature Medicine · 2019 · 695 citations

Tumor Biology, Cell Autophagy, Pancreatic Cancer +9

Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells

Marc A. Antonyak, Bo Li, Lindsey K. Boroughs et al. · Proceedings of the National Academy of Sciences · 2011 · 489 citations · Full text

Extracellular Microvesicles, Horizontal Transfer, Cancer Biology +19

Long-Term ERK Inhibition in KRAS-Mutant Pancreatic Cancer Is Associated with MYC Degradation and Senescence-like Growth Suppression

Tikvah K. Hayes, Nicole F. Neel, Chaoxin Hu et al. · Cancer Cell · 2015 · 271 citations · Full text

Oncology, Pancreatic Cancer, Long-term Erk Inhibition +10

Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer

G. Aaron Hobbs, Nicole M. Baker, Anne M. Miermont et al. · Cancer Discovery · 2019 · 210 citations · Full text

KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism

Angelina V. Vaseva, Devon R. Blake, Thomas S.K. Gilbert et al. · Cancer Cell · 2018 · 186 citations · Full text

Reductive Stress, Signal Transduction, Biochemistry +13