Nicolas M. Kosa

Discovering de novo peptide substrates for enzymes using machine learning

Lorillee Tallorin, Jialei Wang, Woojoo E. Kim et al. · Nature Communications · 2018 · 82 citations · Full text

Life Sciences, Biochemistry, Chemical Biology +17

4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-<i>N</i>-(4-methoxypyridin-2-yl)piperazine-1-carbothioamide (ML267), a Potent Inhibitor of Bacterial Phosphopantetheinyl Transferase That Attenuates Secondary Metabolism and Thwarts Bacterial Growth

Timothy L. Foley, Ganesha Rai, Adam Yasgar et al. · Journal of Medicinal Chemistry · 2014 · 58 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Reversible labeling of native and fusion-protein motifs

Nicolas M. Kosa, Robert W. Haushalter, Andrew R. Smith et al. · Nature Methods · 2012 · 45 citations

Life Sciences, Biochemistry, Molecular Biology +12

Fluorescent techniques for discovery and characterization of phosphopantetheinyl transferase inhibitors

Nicolas M. Kosa, Timothy L. Foley, Michael D. Burkart · The Journal of Antibiotics · 2013 · 18 citations · Full text

Pharmacy, Biochemistry, Medicinal Chemistry +13

Chemoenzymatic exchange of phosphopantetheine on protein and peptide

Nicolas M. Kosa, Kevin Pham, Michael D. Burkart · Chemical Science · 2014 · 17 citations

Life Sciences, Biochemistry, Microbiology +13