Hitomi Nishinakamura

The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies

Shogo Kumagai, Yosuke Togashi, Takahiro Kamada et al. · Nature Immunology · 2020 · 785 citations

Cancer Immunosurveillance, Autoimmune Disease, T-regulatory Cell +12

Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments

Shogo Kumagai, Shohei Koyama, Kota Itahashi et al. · Cancer Cell · 2022 · 752 citations

Cancer Immunosurveillance, Pd-1 Expression, Medicine +11

Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity

Hiroyuki Mori, Reiko Hanada, Toshikatsu Hanada et al. · Nature Medicine · 2004 · 645 citations

Obesity, Metabolic Syndrome, Energy Homeostasis +13

Hyaluronan Oligosaccharides Induce CD44 Cleavage and Promote Cell Migration in CD44-expressing Tumor Cells

Kazuki N. Sugahara, Toshiyuki Murai, Hitomi Nishinakamura et al. · Journal of Biological Chemistry · 2003 · 202 citations · Full text

Engagement of CD44 Promotes Rac Activation and CD44 Cleavage during Tumor Cell Migration

Toshiyuki Murai, Yoshihiro Miyazaki, Hitomi Nishinakamura et al. · Journal of Biological Chemistry · 2004 · 145 citations · Full text