Ronald Wegrzyn

Discovery of GSK2126458, a Highly Potent Inhibitor of PI3K and the Mammalian Target of Rapamycin

Steven D. Knight, Nicholas D. Adams, Joelle L. Burgess et al. · ACS Medicinal Chemistry Letters · 2010 · 367 citations · Full text

Highly Potent Inhibitor, Tumor Biology, Mammalian Target +16

Identification of HPV-16 E7 peptides that are potent antagonists of E7 binding to the retinoblastoma suppressor protein.

Raymond E. Jones, Ronald Wegrzyn, Denis R. Patrick et al. · Journal of Biological Chemistry · 1990 · 85 citations · Full text

Immunology, Complex Formation, Viral Structural Protein +19

Structure-function analysis of synthetic and recombinant derivatives of transforming growth factor alpha.

Deborah Defeo-Jones, J Y Tai, Ronald Wegrzyn et al. · Molecular and Cellular Biology · 1988 · 57 citations · Full text

Human Growth, Molecular Biology, Growth Factor Alpha +19

Substitution of lysine for arginine at position 42 of human transforming growth factor-alpha eliminates biological activity without changing internal disulfide bonds.

Deborah Defeo-Jones, J Y Tai, Gerald A. Vuocolo et al. · Molecular and Cellular Biology · 1989 · 42 citations · Full text

Epidermal Growth Factor, Human Growth, Cell Growth +19

Specific N-methylations of HPV-16 E7 peptides alter binding to the retinoblastoma suppressor protein.

Raymond E. Jones, David Heimbrook, Hans E. Huber et al. · Journal of Biological Chemistry · 1992 · 29 citations · Full text

Hpv-16 E7, Cancer-associated Virus, Cervical Cancer +14