Concepedia

David Heimbrook

DH

66

Publications

6.4K

Citations

41

H-Index

1981

Active since

Affiliations

United States Military Academy(Current)

La Roche College

Merck & Co., Inc., Rahway, NJ, USA (United States)

MicroDiscovery (Germany)

Yale University

David Heimbrook is an author at United States Military Academy specializing in medicine, pharmacology, and cell biology.

Top concepts

MedicineCell BiologyPharmacologyNatural SciencesTumor BiologyBiochemistryDrug DiscoveryMolecular BiologyCell SignalingCancer Research

Publications per year

1981–2014

66

Publications

66

Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1

Lyubomir T. Vassilev, Christian Tovar, Shaoqing Chen et al. · Proceedings of the National Academy of Sciences · 2006 · 804 citations · Full text

Cdk1 Inhibition, Immunology, Human Cdk1 +17

Small-molecule MDM2 antagonists reveal aberrant p53 signaling in cancer: Implications for therapy

Christian Tovar, James Rosinski, Zoran Filipovic et al. · Proceedings of the National Academy of Sciences · 2006 · 699 citations · Full text

Chemoprevention Strategy, Apoptosis, Cell Death +17

RG7204 (PLX4032), a Selective BRAFV600E Inhibitor, Displays Potent Antitumor Activity in Preclinical Melanoma Models

Hong Yang, Brian Higgins, Kenneth Kolinsky et al. · Cancer Research · 2010 · 400 citations

Melanoma Cell Lines, Phase Ii, Medicine +15

Evaluation of farnesyl:protein transferase and geranylgeranyl:protein transferase inhibitor combinations in preclinical models.

Robert B. Lobell, CharlesA. Omer, Marc Abrams et al. · PubMed · 2001 · 239 citations

Protein Transferase, H Infusion, Chemical Biology +18

Phosphorylation of p53 on Key Serines Is Dispensable for Transcriptional Activation and Apoptosis

Thelma Thompson, Christian Tovar, Hong Yang et al. · Journal of Biological Chemistry · 2004 · 233 citations · Full text

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