Concepedia
Statistics
Publications
66
Citations
6.4K
H-Index
41
Active since
1981
Affiliations
United States Military Academy(Current)
La Roche College
Merck & Co., Inc., Rahway, NJ, USA (United States)
MicroDiscovery (Germany)
Yale University
David Heimbrook is an author at United States Military Academy specializing in medicine, pharmacology, and cell biology.
Top concepts
MedicineCell BiologyPharmacologyNatural SciencesTumor BiologyBiochemistryDrug DiscoveryMolecular BiologyCell SignalingCancer Research
Publications per year
1981–2014
Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1
Lyubomir T. Vassilev, Christian Tovar, Shaoqing Chen et al. · Proceedings of the National Academy of Sciences · 2006 · 804 citations · Full text
Cdk1 Inhibition, Immunology, Human Cdk1 +17
Small-molecule MDM2 antagonists reveal aberrant p53 signaling in cancer: Implications for therapy
Christian Tovar, James Rosinski, Zoran Filipovic et al. · Proceedings of the National Academy of Sciences · 2006 · 699 citations · Full text
Chemoprevention Strategy, Apoptosis, Cell Death +17
RG7204 (PLX4032), a Selective BRAFV600E Inhibitor, Displays Potent Antitumor Activity in Preclinical Melanoma Models
Hong Yang, Brian Higgins, Kenneth Kolinsky et al. · Cancer Research · 2010 · 400 citations
Melanoma Cell Lines, Phase Ii, Medicine +15
Evaluation of farnesyl:protein transferase and geranylgeranyl:protein transferase inhibitor combinations in preclinical models.
Robert B. Lobell, CharlesA. Omer, Marc Abrams et al. · PubMed · 2001 · 239 citations
Protein Transferase, H Infusion, Chemical Biology +18
Phosphorylation of p53 on Key Serines Is Dispensable for Transcriptional Activation and Apoptosis
Thelma Thompson, Christian Tovar, Hong Yang et al. · Journal of Biological Chemistry · 2004 · 233 citations · Full text
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