Raymond E. Jones

Allosteric Akt (PKB) inhibitors: discovery and SAR of isozyme selective inhibitors

Craig W. Lindsley, Zhijian Zhao, William Leister et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 497 citations · Full text

Allosteric Akt, Medicinal Chemistry, Drug Target +9

Identification and characterization of pleckstrin-homology-domain-dependent and isoenzyme-specific Akt inhibitors

Stanley F. Barnett, Deborah Defeo-Jones, Sheng Fu et al. · Biochemical Journal · 2005 · 394 citations · Full text

Cloning of cDNAs for cellular proteins that bind to the retinoblastoma gene product

Deborah Defeo-Jones, Pearl S. Huang, Raymond E. Jones et al. · Nature · 1991 · 332 citations

Cell Regulation, Natural Sciences, Molecular Biology +8

Tumor cell sensitization to apoptotic stimuli by selective inhibition of specific Akt/PKB family members

Deborah Defeo-Jones, Stanley F. Barnett, Sheng Fu et al. · Molecular Cancer Therapeutics · 2005 · 174 citations

Chemoprevention Strategy, Family Members, Apoptosis +20

A peptide–doxorubicin 'prodrug' activated by prostate-specific antigen selectively kills prostate tumor cells positive for prostate-specific antigen in vivo

Deborah Defeo-Jones, Victor M. Garsky, Bradley K. Wong et al. · Nature Medicine · 2000 · 156 citations

Urology, Prostate Tumor Cells, Medicine +8