Wendy Dangerfield

In vitro and in vivo reversal of P-glycoprotein-mediated multidrug resistance by a novel potent modulator, XR9576.

Prakash Mistry, Alistair Stewart, Wendy Dangerfield et al. · PubMed · 2001 · 350 citations

Pharmacotherapy, Tumor Biology, P-glycoprotein-mediated Multidrug Resistance +17

Reversal of P-glycoprotein mediated multidrug resistance by novel anthranilamide derivatives

Michael W. Roe, Adrian Folkes, Philip J. Ashworth et al. · Bioorganic & Medicinal Chemistry Letters · 1999 · 164 citations

Molecular Pharmacology, Medicinal Chemistry, Pharmaceutical Science +12

Structure−Activity Relationships for Pyrido-, Imidazo-, Pyrazolo-, Pyrazino-, and Pyrrolophenazinecarboxamides as Topoisomerase-Targeted Anticancer Agents

Swarna A. Gamage, Julie A. Spicer, Gordon W. Rewcastle et al. · Journal of Medicinal Chemistry · 2002 · 145 citations

Pharmaceutical Science, Pharmacotherapy, Pharmaceutical Chemistry +16

Novel Angular Benzophenazines:  Dual Topoisomerase I and Topoisomerase II Inhibitors as Potential Anticancer Agents

Nigel Vicker, Luke Burgess, Irina Chuckowree et al. · Journal of Medicinal Chemistry · 2002 · 131 citations

Medicinal Chemistry, Pharmaceutical Chemistry, Bioorganic Chemistry +15

In vitro and in vivo characterization of XR11576, a novel, orally active, dual inhibitor of topoisomerase I and II

Prakash Mistry, Alistair Stewart, Wendy Dangerfield et al. · Anti-Cancer Drugs · 2002 · 62 citations