Jorge Becerril

Design and Application of an α‐Helix‐Mimetic Scaffold Based on an Oligoamide‐Foldamer Strategy: Antagonism of the Bak BH3/Bcl‐xL Complex

Justin T. Ernst, Jorge Becerril, Hyung Soon Park et al. · Angewandte Chemie International Edition · 2003 · 264 citations

Supramolecular Assembly, Apoptosis, Molecular Biology +19

Synthetic α‐Helix Mimetics as Agonists and Antagonists of Islet Amyloid Polypeptide Aggregation

Ishu Saraogi, James A. Hebda, Jorge Becerril et al. · Angewandte Chemie International Edition · 2009 · 129 citations · Full text

Molecular Pharmacology, Hiapp=human Iapp, Biochemistry +14

The BH3 α-Helical Mimic BH3-M6 Disrupts Bcl-XL, Bcl-2, and MCL-1 Protein-Protein Interactions with Bax, Bak, Bad, or Bim and Induces Apoptosis in a Bax- and Bim-dependent Manner

Aslamuzzaman Kazi, Jiazhi Sun, Kenichiro Doi et al. · Journal of Biological Chemistry · 2010 · 120 citations · Full text

Mcl-1 Protein-protein Interactions, Apoptosis, Immunology +17

Efficient Macrocyclization of U-Turn Preorganized Peptidomimetics:  The Role of Intramolecular H-Bond and Solvophobic Effects

Jorge Becerril, Michael Bolte, M. Isabel Burguete et al. · Journal of the American Chemical Society · 2003 · 112 citations

Helix Mimetics as Inhibitors of the Interaction of the Estrogen Receptor with Coactivator Peptides

Jorge Becerril, Andrew D. Hamilton · Angewandte Chemie International Edition · 2007 · 98 citations · Full text

Estrogen Receptor, Molecular Biology, Peptide Science +21