James A. Hebda

Conserved and Cooperative Assembly of Membrane-Bound α-Helical States of Islet Amyloid Polypeptide

Jefferson D. Knight, James A. Hebda, Andrew D. Miranker · Biochemistry · 2006 · 309 citations

Proteinlipid Interaction, Cooperative Assembly, Protein Assembly +16

Synthetic α‐Helix Mimetics as Agonists and Antagonists of Islet Amyloid Polypeptide Aggregation

Ishu Saraogi, James A. Hebda, Jorge Becerril et al. · Angewandte Chemie International Edition · 2009 · 129 citations · Full text

Molecular Pharmacology, Hiapp=human Iapp, Biochemistry +14

A Peptidomimetic Approach to Targeting Pre-amyloidogenic States in Type II Diabetes

James A. Hebda, Ishu Saraogi, Mazin Magzoub et al. · Chemistry & Biology · 2009 · 101 citations · Full text

Peptidomimetic Approach, Alzheimer's Disease, Biochemistry +11

Islet Amyloid-Induced Cell Death and Bilayer Integrity Loss Share a Molecular Origin Targetable with Oligopyridylamide-Based α-Helical Mimetics

Sunil Kumar, Diana E. Schlamadinger, Mark A. Brown et al. · Chemistry & Biology · 2015 · 67 citations · Full text

Engineering, Biochemistry, Peptide Engineering +6

Amide inequivalence in the fibrillar assembly of islet amyloid polypeptide

Bon W. Koo, James A. Hebda, Andrew D. Miranker · Protein Engineering Design and Selection · 2008 · 58 citations · Full text

Protein Function, Amyloid Fibers, Protein Assembly +11