J Gosset

Application of PBPK modelling in drug discovery and development at Pfizer

Hannah M. Jones, Maurice Dickins, Kuresh Youdim et al. · Xenobiotica · 2011 · 93 citations

Inhibition of TRPM8 Channels Reduces Pain in the Cold Pressor Test in Humans

Wendy J. Winchester, Katrina Gore, Sophie Glatt et al. · Journal of Pharmacology and Experimental Therapeutics · 2014 · 90 citations

Discovery and Optimization of Imidazopyridine-Based Inhibitors of Diacylglycerol Acyltransferase 2 (DGAT2)

Kentaro Futatsugi, Daniel W. Kung, Suvi T. M. Orr et al. · Journal of Medicinal Chemistry · 2015 · 80 citations

Combinatorial Chemistry, Lipid Analysis, Medicinal Chemistry +14

Towards in vitro models for reducing or replacing the use of animals in drug testing

David M. Stresser, Anna K. Kopec, Philip Hewitt et al. · Nature Biomedical Engineering · 2023 · 75 citations

Animal Testing, Xenotransplantation, Preclinical Drug Evaluation +11

A high-throughput microfluidic microphysiological system (PREDICT-96) to recapitulate hepatocyte function in dynamic, re-circulating flow conditions

Kelly Tan, Philip M. Keegan, Miles Rogers et al. · Lab on a Chip · 2019 · 73 citations