Philip M. Keegan

High-throughput organ-on-chip platform with integrated programmable fluid flow and real-time sensing for complex tissue models in drug development workflows

Hesham Azizgolshani, Jonathan Coppeta, Else M. Vedula et al. · Lab on a Chip · 2021 · 203 citations · Full text

Engineering, Organ-on-a-chip, Complex Tissue Models +16

Acid sphingomyelinase is activated in sickle cell erythrocytes and contributes to inflammatory microparticle generation in SCD

Anthony O. Awojoodu, Philip M. Keegan, Alicia R. Lane et al. · Blood · 2014 · 93 citations · Full text

A high-throughput microfluidic microphysiological system (PREDICT-96) to recapitulate hepatocyte function in dynamic, re-circulating flow conditions

Kelly Tan, Philip M. Keegan, Miles Rogers et al. · Lab on a Chip · 2019 · 73 citations

Manipulating substrate and pH in zymography protocols selectively distinguishes cathepsins K, L, S, and V activity in cells and tissues

Catera L. Wilder, Keon-Young Park, Philip M. Keegan et al. · Archives of Biochemistry and Biophysics · 2011 · 67 citations

V Activity, Biochemistry, Medicine +11

A high-throughput microfluidic bilayer co-culture platform to study endothelial-pericyte interactions

Miles Rogers, Ashley L. Gard, Robert B. Gaibler et al. · Scientific Reports · 2021 · 46 citations · Full text