Senthil Velan Bhoopalan

Ex vivo prime editing of patient haematopoietic stem cells rescues sickle-cell disease phenotypes after engraftment in mice

Kelcee A. Everette, Gregory A. Newby, Rachel M. Levine et al. · Nature Biomedical Engineering · 2023 · 125 citations · Full text

Erythropoietin regulation of red blood cell production: from bench to bedside and back

Senthil Velan Bhoopalan, Lily Huang, Mitchell J. Weiss · F1000Research · 2020 · 110 citations · Full text

Potent and uniform fetal hemoglobin induction via base editing

Thiyagaraj Mayuranathan, Gregory A. Newby, Ruopeng Feng et al. · Nature Genetics · 2023 · 67 citations · Full text

Base Editing, Developmental Biology, Fetal Medicine +2

An RPS19-edited model for Diamond-Blackfan anemia reveals TP53-dependent impairment of hematopoietic stem cell activity

Senthil Velan Bhoopalan, Jonathan Yen, Thiyagaraj Mayuranathan et al. · JCI Insight · 2022 · 34 citations · Full text

Immunology, Blood Cell, Rps19-edited Model +19

Integrative proteomics reveals principles of dynamic phosphosignaling networks in human erythropoiesis

Özge Karayel, Peng Xu, Isabell Bludau et al. · Molecular Systems Biology · 2020 · 30 citations · Full text