Kelcee A. Everette

Engineered pegRNAs improve prime editing efficiency

James W. Nelson, Peyton B. Randolph, Simon P. Shen et al. · Nature Biotechnology · 2021 · 671 citations · Full text

Natural Sciences, Molecular Biology, Gene Editing +5

Base editing of haematopoietic stem cells rescues sickle cell disease in mice

Gregory A. Newby, Jonathan Yen, Kaitly J. Woodard et al. · Nature · 2021 · 353 citations · Full text

Base Editing, Cell Therapy, Haematopoietic Stem Cells +9

Phage-assisted evolution and protein engineering yield compact, efficient prime editors

Jordan L. Doman, Smriti Pandey, Monica E. Neugebauer et al. · Cell · 2023 · 245 citations · Full text

Ex vivo prime editing of patient haematopoietic stem cells rescues sickle-cell disease phenotypes after engraftment in mice

Kelcee A. Everette, Gregory A. Newby, Rachel M. Levine et al. · Nature Biomedical Engineering · 2023 · 125 citations · Full text

Human T cell generation is restored in CD3δ severe combined immunodeficiency through adenine base editing

Grace E. McAuley, Gloria Yiu, Patrick Chang et al. · Cell · 2023 · 75 citations · Full text

Human Retrovirus, T-regulatory Cell, Immunology +7