Peng Xu

c-Jun overexpression in CAR T cells induces exhaustion resistance

Rachel C. Lynn, Evan W. Weber, Elena Sotillo et al. · Nature · 2019 · 831 citations · Full text

Physiology, Autoimmunity, Tolerance Induction +6

Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors

Johanna Theruvath, Elena Sotillo, Christopher Mount et al. · Nature Medicine · 2020 · 288 citations · Full text

Cancer Immunosurveillance, Medicine, Immunology +8

Co-opting signalling molecules enables logic-gated control of CAR T cells

Aidan M. Tousley, Maria Caterina Rotiroti, Louai Labanieh et al. · Nature · 2023 · 251 citations · Full text

Car T Cells, Signal Transduction, Cell Control +9

Anti-GD2 synergizes with CD47 blockade to mediate tumor eradication

Johanna Theruvath, Marie Ménard, Benjamin Smith et al. · Nature Medicine · 2022 · 239 citations · Full text

Tumor Eradication, Immunology, Immune Checkpoint Inhibitor +3

Acute depletion of CTCF directly affects MYC regulation through loss of enhancer–promoter looping

Judith Hyle, Yang Zhang, Shaela Wright et al. · Nucleic Acids Research · 2019 · 152 citations · Full text

Enhancer–promoter Looping, Molecular Regulation, Transcriptional Regulation +23