Rachel C. Lynn

c-Jun overexpression in CAR T cells induces exhaustion resistance

Rachel C. Lynn, Evan W. Weber, Elena Sotillo et al. · Nature · 2019 · 893 citations · Full text

Life Sciences, Cell Biology, Immunology +16

Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling

Evan W. Weber, Kevin R. Parker, Elena Sotillo et al. · Science · 2021 · 599 citations · Full text

Medicine, Immunology, Oncology +17

Tuning the Antigen Density Requirement for CAR T-cell Activity

Robbie G. Majzner, Skyler P. Rietberg, Elena Sotillo et al. · Cancer Discovery · 2020 · 579 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

CAR T cells with dual targeting of CD19 and CD22 in adult patients with recurrent or refractory B cell malignancies: a phase 1 trial

Jay Y. Spiegel, Shabnum Patel, Lori Muffly et al. · Nature Medicine · 2021 · 572 citations · Full text

Medicine, Hematology, Oncology +17

A Universal Strategy for Adoptive Immunotherapy of Cancer through Use of a Novel T-cell Antigen Receptor

Katarzyna Urbańska, Evripidis Lanitis, Mathilde Poussin et al. · Cancer Research · 2012 · 329 citations · Full text

Life Sciences, Immunology, Oncology +17