Bruce W. Konicek

The Protein Kinase Cβ–Selective Inhibitor, Enzastaurin (LY317615.HCl), Suppresses Signaling through the AKT Pathway, Induces Apoptosis, and Suppresses Growth of Human Colon Cancer and Glioblastoma Xenografts

Jeremy R. Graff, Ann M. McNulty, Kimberly R. Hanna et al. · Cancer Research · 2005 · 437 citations · Full text

Medicine, Oncology, Pharmacology +15

Increased AKT Activity Contributes to Prostate Cancer Progression by Dramatically Accelerating Prostate Tumor Growth and Diminishing p27Kip1 Expression

Jeremy R. Graff, Bruce W. Konicek, Ann M. McNulty et al. · Journal of Biological Chemistry · 2000 · 380 citations · Full text

Medicine, Molecular Biology, Oncology +15

Therapeutic suppression of translation initiation factor eIF4E expression reduces tumor growth without toxicity

Jeremy R. Graff, Bruce W. Konicek, Thomas M. Vincent et al. · Journal of Clinical Investigation · 2007 · 379 citations · Full text

Medicine, Cancer Biology, Oncology +17

eIF4E Activation Is Commonly Elevated in Advanced Human Prostate Cancers and Significantly Related to Reduced Patient Survival

Jeremy R. Graff, Bruce W. Konicek, Rebecca L. Lynch et al. · Cancer Research · 2009 · 199 citations

Medicine, Molecular Biology, Oncology +17

Pharmacogenetic Inhibition of eIF4E-Dependent Mmp9 mRNA Translation Reverses Fragile X Syndrome-like Phenotypes

Christos G. Gkogkas, Arkady Khoutorsky, Ruifeng Cao et al. · Cell Reports · 2014 · 199 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17