Rebecca L. Lynch

The Protein Kinase Cβ–Selective Inhibitor, Enzastaurin (LY317615.HCl), Suppresses Signaling through the AKT Pathway, Induces Apoptosis, and Suppresses Growth of Human Colon Cancer and Glioblastoma Xenografts

Jeremy R. Graff, Ann M. McNulty, Kimberly R. Hanna et al. · Cancer Research · 2005 · 437 citations · Full text

Medicine, Oncology, Pharmacology +15

Therapeutic suppression of translation initiation factor eIF4E expression reduces tumor growth without toxicity

Jeremy R. Graff, Bruce W. Konicek, Thomas M. Vincent et al. · Journal of Clinical Investigation · 2007 · 379 citations · Full text

Medicine, Cancer Biology, Oncology +17

eIF4E Activation Is Commonly Elevated in Advanced Human Prostate Cancers and Significantly Related to Reduced Patient Survival

Jeremy R. Graff, Bruce W. Konicek, Rebecca L. Lynch et al. · Cancer Research · 2009 · 199 citations

Medicine, Molecular Biology, Oncology +17

The Progression of LNCaP Human Prostate Cancer Cells to Androgen Independence Involves Decreased FOXO3a Expression and Reduced <i>p27KIP1</i> Promoter Transactivation

Rebecca L. Lynch, Bruce W. Konicek, Ann M. McNulty et al. · Molecular Cancer Research · 2005 · 78 citations

Medicine, Molecular Biology, Oncology +15

The selective estrogen receptor modulator trioxifene (LY133314) inhibits metastasis and extends survival in the PAIII rat prostatic carcinoma model.

Blake Lee Neubauer, Ann M. McNulty, Márcio F. Chedid et al. · PubMed · 2003 · 44 citations

Medicine, Oncology, Pharmacology +14