Christina George

Dual Targeting of Epithelial Ovarian Cancer Via Folate Receptor α and the Proton-Coupled Folate Transporter with 6-Substituted Pyrrolo[2,3- <i>d</i> ]pyrimidine Antifolates

Zhanjun Hou, Leda Gattoc, Carrie O’Connor et al. · Molecular Cancer Therapeutics · 2017 · 40 citations · Full text

6-Substituted Pyrrolo[2,3-<i>d</i>]pyrimidine Thienoyl Regioisomers as Targeted Antifolates for Folate Receptor α and the Proton-Coupled Folate Transporter in Human Tumors

Lei Wang, Adrianne Wallace-Povirk, Sudhir Raghavan et al. · Journal of Medicinal Chemistry · 2015 · 38 citations · Full text

Chemical Biology, Pharmaceutical Chemistry, Tumor Biology +19

First-in-Class Phosphorylated-p68 Inhibitor RX-5902 Inhibits β-Catenin Signaling and Demonstrates Antitumor Activity in Triple-Negative Breast Cancer

Anna Capasso, Stacey M. Bagby, Kyrie L. Dailey et al. · Molecular Cancer Therapeutics · 2019 · 29 citations · Full text

Structure–Activity Profiles of Novel 6-Substituted Pyrrolo[2,3-<i>d</i>]pyrimidine Thienoyl Antifolates with Modified Amino Acids for Cellular Uptake by Folate Receptors α and β and the Proton-Coupled Folate Transporter

Lalit K. Golani, Christina George, Sai Zhao et al. · Journal of Medicinal Chemistry · 2014 · 26 citations · Full text

Novel 5-Substituted Pyrrolo[2,3-<i>d</i>]pyrimidines as Dual Inhibitors of Glycinamide Ribonucleotide Formyltransferase and 5-Aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase and as Potential Antitumor Agents

Yiqiang Wang, Shermaine Mitchell-Ryan, Sudhir Raghavan et al. · Journal of Medicinal Chemistry · 2015 · 25 citations · Full text