Adrianne Wallace-Povirk

Author

Duquesne University ORCID

Also Known As

A. Wallace, A. Wallace-Povirk, Adrianne C. Wallace-Povirk, Adrianne Wallace, Adrianne Wallace-Povirk, Andrew Wallace

Publications

476

Citations

H-Index

Concepts

All Affiliations

Duquesne University Wayne State University The Barbara Ann Karmanos Cancer Institute Indiana University Bloomington Fred Hutch Cancer Center

About

Adrianne Wallace-Povirk is an author at Duquesne University specializing in drug discovery, medicinal chemistry, and natural sciences.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	3	3	81
2	Natural Sciences	3	3	81
3	Biochemistry	3	3	81
4	Pharmacology	3	3	81
5	Chemical Biology	1	1	38

Adrianne Wallace-Povirk

Publications

383

Citations

H-Index

Page 1

	Year	Citations
Novel Pyrrolo[3,2- <i>d</i> ]pyrimidine Compounds Target Mitochondrial and Cytosolic One-carbon Metabolism with Broad-spectrum Antitumor Efficacy Aamod S. Dekhne, Khushbu Shah, Gregory S. Ducker, Molecular Cancer Therapeutics	2019	51
Dual Targeting of Epithelial Ovarian Cancer Via Folate Receptor α and the Proton-Coupled Folate Transporter with 6-Substituted Pyrrolo[2,3- <i>d</i> ]pyrimidine Antifolates Zhanjun Hou, Leda Gattoc, Carrie O’Connor, Molecular Cancer Therapeutics	2017	40
6-Substituted Pyrrolo[2,3-<i>d</i>]pyrimidine Thienoyl Regioisomers as Targeted Antifolates for Folate Receptor α and the Proton-Coupled Folate Transporter in Human Tumors Lei Wang, Adrianne Wallace-Povirk, Sudhir Raghavan, Journal of Medicinal Chemistry Chemical BiologyPharmaceutical ChemistryTumor BiologyMolecular PharmacologyMedicinal Chemistry	2015	38
Cellular Pharmacodynamics of a Novel Pyrrolo[3,2-d]pyrimidine Inhibitor Targeting Mitochondrial and Cytosolic One-Carbon Metabolism Aamod S. Dekhne, Changwen Ning, Md. Junayed Nayeen, Molecular Pharmacology	2019	35
Different effects of valproic acid on photoreceptor loss in Rd1 and Rd10 retinal degeneration mice. Kenneth P. Mitton, Alvaro Guzman, Mrinalini Deshpande, PubMed	2014	32
Tumor Targeting with Novel 6-Substituted Pyrrolo [2,3-<i>d</i>] Pyrimidine Antifolates with Heteroatom Bridge Substitutions via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis Lalit K. Golani, Adrianne Wallace-Povirk, S.M. Deis, Journal of Medicinal Chemistry Pharmaceutical ChemistryTumor BiologyMedicinal ChemistryCarbon VicinalCellular Uptake	2016	31
Folate transporter dynamics and therapy with classic and tumor-targeted antifolates Carrie O’Connor, Adrianne Wallace-Povirk, Changwen Ning, Scientific Reports	2021	31
Structure–Activity Profiles of Novel 6-Substituted Pyrrolo[2,3-<i>d</i>]pyrimidine Thienoyl Antifolates with Modified Amino Acids for Cellular Uptake by Folate Receptors α and β and the Proton-Coupled Folate Transporter Lalit K. Golani, Christina George, Sai Zhao, Journal of Medicinal Chemistry	2014	26
Fluorine-Substituted Pyrrolo[2,3-<i>d</i>]Pyrimidine Analogues with Tumor Targeting via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of<i>de Novo</i>Purine Nucleotide Biosynthesis Manasa Ravindra, Mike R. Wilson, Nian Tong, Journal of Medicinal Chemistry	2018	26
Targeted therapy of pyrrolo[2,3-d]pyrimidine antifolates in a syngeneic mouse model of high grade serous ovarian cancer and the impact on the tumor microenvironment Adrianne Wallace-Povirk, Lisa Rubinsak, Agnes Malysa, Scientific Reports	2022	14

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