Aamod S. Dekhne

Novel Pyrrolo[3,2- <i>d</i> ]pyrimidine Compounds Target Mitochondrial and Cytosolic One-carbon Metabolism with Broad-spectrum Antitumor Efficacy

Aamod S. Dekhne, Khushbu Shah, Gregory S. Ducker et al. · Molecular Cancer Therapeutics · 2019 · 51 citations · Full text

Cellular Pharmacodynamics of a Novel Pyrrolo[3,2-d]pyrimidine Inhibitor Targeting Mitochondrial and Cytosolic One-Carbon Metabolism

Aamod S. Dekhne, Changwen Ning, Md. Junayed Nayeen et al. · Molecular Pharmacology · 2019 · 35 citations · Full text

Design, synthesis and biological evaluation of novel pyrrolo[2,3-d]pyrimidine as tumor-targeting agents with selectivity for tumor uptake by high affinity folate receptors over the reduced folate carrier

Lalit K. Golani, Farhana Islam, Carrie O’Connor et al. · Bioorganic & Medicinal Chemistry · 2020 · 12 citations · Full text

Drug Targeting, Reduced Folate Carrier, Medicine +9

Mitochondrial and Cytosolic One-Carbon Metabolism Is a Targetable Metabolic Vulnerability in Cisplatin-Resistant Ovarian Cancer

Adrianne Wallace-Povirk, Carrie O’Connor, Aamod S. Dekhne et al. · Molecular Cancer Therapeutics · 2024 · 11 citations · Full text