Tinyi Chu

Ibuprofen Suppresses Plaque Pathology and Inflammation in a Mouse Model for Alzheimer's Disease

Giselle P. Lim, Fu Yang, Tinyi Chu et al. · Journal of Neuroscience · 2000 · 880 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Cell type and gene expression deconvolution with BayesPrism enables Bayesian integrative analysis across bulk and single-cell RNA sequencing in oncology

Tinyi Chu, Zhong Wang, Dana Pe’er et al. · Nature Cancer · 2022 · 624 citations · Full text

Life Sciences, Cancer Biology, Oncology +17

The demethylenation of methylenedioxymethamphetamine (“ecstasy”) by debrisoquine hydroxylase (CYP2D6)

Geoffrey T. Tucker, M. S. Lennard, S. W. Ellis et al. · Biochemical Pharmacology · 1994 · 236 citations

Medicine, Pharmacology, Toxicology +12

Transcriptional response to stress is pre-wired by promoter and enhancer architecture

Anniina Vihervaara, Dig Bijay Mahat, Michael J. Guertin et al. · Nature Communications · 2017 · 185 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Chromatin run-on and sequencing maps the transcriptional regulatory landscape of glioblastoma multiforme

Tinyi Chu, Edward J. Rice, Gregory T. Booth et al. · Nature Genetics · 2018 · 166 citations

Medicine, Molecular Biology, Oncology +14