Base-pair-resolution genome-wide mapping of active RNA polymerases using precision nuclear run-on (PRO-seq)

Dig Bijay Mahat, Hojoong Kwak, Gregory T. Booth, +6

Nature Protocols

Natural SciencesGeneticsBase-pair-resolution Genome-wide MappingRna BiologyMolecular Biology +3

A Cdk9–PP1 switch regulates the elongation–termination transition of RNA polymerase II

Pabitra K. Parua, Gregory T. Booth, Miriam Sansó, +4

Nature

Transcriptional RegulationElongation–termination TransitionEngineeringCdk9–pp1 SwitchRna Polymerase Ii +8

Chromatin run-on and sequencing maps the transcriptional regulatory landscape of glioblastoma multiforme

Tinyi Chu, Edward J. Rice, Gregory T. Booth, +9

Nature Genetics

Neuro-oncologyChromatinTranscriptional Regulatory LandscapeGlioblastoma MultiformeTumor Heterogeneity +9

Divergence of a conserved elongation factor and transcription regulation in budding and fission yeast

Gregory T. Booth, Isabel X. Wang, Vivian G. Cheung, +1

Genome Research

GeneticsSpt4 RevealMolecular BiologyMolecular GeneticsGene Regulatory Network +15

Cdk9 regulates a promoter-proximal checkpoint to modulate RNA polymerase II elongation rate in fission yeast

Gregory T. Booth, Pabitra K. Parua, Miriam Sansó, +2

Nature Communications

Nascent RNA sequencing reveals a dynamic global transcriptional response at genes and enhancers to the natural medicinal compound celastrol

Noah Dukler, Gregory T. Booth, Yi-Fei Huang, +5

Genome Research

EngineeringMolecular RegulationGeneticsMolecular BiologyTranscriptomics Technology +17

The NELF pausing checkpoint mediates the functional divergence of Cdk9

Michael DeBerardine, Gregory T. Booth, Philip Versluis, +1

Nature Communications

RNA polymerase mapping in plants identifies intergenic regulatory elements enriched in causal variants

Roberto Lozano, Gregory T. Booth, Bilan Yonis Omar, +5

G3 Genes Genomes Genetics

PPP1CC2 can form a kinase/phosphatase complex with the testis-specific proteins TSSK1 and TSKS in the mouse testis

Graham MacLeod, Peng Shang, Gregory T. Booth, +4

Reproduction

SpermatogenesisPpp1cc Mutant TestisGeneticsReproductive BiologyFertilisation +19

Single-cell analysis of chromatin and expression reveals age- and sex-associated alterations in the human heart

David F. Read, Gregory T. Booth, Riza M. Daza, +17

Communications Biology