Concepedia

Author

Ludovic Jean

Centre National de la Recherche ScientifiqueORCID

Also Known As

Aurélie Gernet, Jean, Ludovic, L. Jean, Ludovic Jean

115

Publications

2.8K

Citations

29

H-Index

72

Concepts

All Affiliations

Centre National de la Recherche ScientifiqueUniversité de Rouen NormandieLaboratoire COBRAInstitut National des Sciences Appliquées Rouen NormandieNormandie Université
LJ

About

Ludovic Jean is an author at Centre National de la Recherche Scientifique specializing in medicine, pharmacology, and natural sciences.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

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26

1.7K

2

Natural Sciences

21

21

1.5K

3

Biochemistry

21

23

1.5K

4

Engineering

8

8

384

5

Health Sciences

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Ludovic Jean

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45

Publications

2.7K

Citations

29

H-Index

YearCitations

Crystal structures of human cholinesterases in complex with huprine W and tacrine: elements of specificity for anti-Alzheimer's drugs targeting acetyl- and butyryl-cholinesterase

Florian Nachon, E. Carletti, Cyril Ronco,

Biochemical Journal

2013

447

Reactivators of Acetylcholinesterase Inhibited by Organophosphorus Nerve Agents

Guillaume Mercey, Tristan Verdelet, Julien Renou,

Accounts of Chemical Research

2012

393

Phosphine-catalyzed enantioselective [3+2] annulations of 2,3-butadienoates with imines

Ludovic Jean, Angéla Marinetti

Tetrahedron Letters

2006

129

Human butyrylcholinesterase produced in insect cells: huprine‐based affinity purification and crystal structure

Xavier Brazzolotto, M. Wandhammer, Cyril Ronco,

FEBS Journal

2012

111

Screening of chiral phosphines as catalysts for the enantioselective [3+2] annulations of N-tosylimines with allenic esters

Nicolas Fleury‐Brégeot, Ludovic Jean, Pascal Retailleau,

Tetrahedron

2007

111

First efficient uncharged reactivators for the dephosphylation of poisoned human acetylcholinesterase

Guillaume Mercey, Tristan Verdelet, Géraldine Saint-André,

Chemical Communications

2011

101

Discovery of a Potent Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase with Antioxidant Activity that Alleviates Alzheimer-like Pathology in Old APP/PS1 Mice

Elisabet Viayna, Nicolas Coquelle, Monika Cieslikiewicz‐Bouet,

Journal of Medicinal Chemistry

2020

88

Concise Total Synthesis of Cruentaren A

Alois Fürstner, Martin Bindl, Ludovic Jean

Angewandte Chemie International Edition

2007

79

Design, synthesis and biological evaluation of novel tetrahydroacridine pyridine- aldoxime and -amidoxime hybrids as efficient uncharged reactivators of nerve agent-inhibited human acetylcholinesterase

Maria Kliachyna, Gianluca Santoni, Valentin Nussbaum,

European Journal of Medicinal Chemistry

2014

77

Design, biological evaluation and X-ray crystallography of nanomolar multifunctional ligands targeting simultaneously acetylcholinesterase and glycogen synthase kinase-3

Killian Oukoloff, Nicolas Coquelle, Manuela Bartolini,

European Journal of Medicinal Chemistry

2019

65

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