Hideya Komatani

Identification of breast cancer resistant protein/mitoxantrone resistance/placenta-specific, ATP-binding cassette transporter as a transporter of NB-506 and J-107088, topoisomerase I inhibitors with an indolocarbazole structure.

Hideya Komatani, Hitoshi Kotani, Yoshikazu Hara et al. · PubMed · 2001 · 100 citations

Drug Resistance Analysis, Chemoprevention Strategy, Biochemistry +14

Imidazopyridine derivatives as potent and selective Polo-like kinase (PLK) inhibitors

Yoshiyuki Satô, Yu Onozaki, T Sugimoto et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 51 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +11

Structures of the PKC-ι kinase domain in its ATP-bound and apo forms reveal defined structures of residues 533–551 in the C-terminal tail and their roles in ATP binding

Tetsuo Takimura, Kenji Kamata, Kazuhiro Fukasawa et al. · Acta Crystallographica Section D Biological Crystallography · 2010 · 49 citations

Protein Assembly, C-terminal Tail, Molecular Biology +20

Sequence-selective DNA cleavage by a topoisomerase I poison, NB-506

Kazuhiro Fukasawa, Hideya Komatani, Yoshikazu Hara et al. · International Journal of Cancer · 1998 · 25 citations

Chromatin, Dna Sequencing, Biochemistry +10

ABCG2 confers resistance to indolocarbazole compounds by ATP-dependent transport

Rinako Nakagawa, Yoshikazu Hara, Hiroharu Arakawa et al. · Biochemical and Biophysical Research Communications · 2002 · 22 citations

Molecular Pharmacology, Biochemistry, Bioenergetics +7