Manolis Pasparakis

Impaired On/Off Regulation of TNF Biosynthesis in Mice Lacking TNF AU-Rich Elements

Dimitris L. Kontoyiannis, Manolis Pasparakis, Theresa T. Pizarro et al. · Immunity · 1999 · 1.3K citations · Full text

Inflammation, Reductive Stress, Knockout Mouse +10

Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury

Yumiko Imai, Keiji Kuba, G. Gregory Neely et al. · Cell · 2008 · 1.3K citations · Full text

Acute Lung Injury, Asthma, Inflammation +10

Immune and inflammatory responses in TNF alpha-deficient mice: a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response.

Manolis Pasparakis, Lena Alexopoulou, Vasso Episkopou et al. · The Journal of Experimental Medicine · 1996 · 1.2K citations · Full text

Lymphocyte Development, Humoral Response, Immunology +18

Synchronized renal tubular cell death involves ferroptosis

Andreas Linkermann, Rachid Skouta, Nina Himmerkus et al. · Proceedings of the National Academy of Sciences · 2014 · 1.1K citations · Full text

Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis

Melanie Fritsch, Saskia Diana Günther, Robin Schwarzer et al. · Nature · 2019 · 1.1K citations

Signal Transduction, Signaling Pathway, Apoptosis +11