Ying‐Jiun Chen

High systemic and tumor-associated IL-8 correlates with reduced clinical benefit of PD-L1 blockade

Kobe Yuen, Lifen Liu, Vinita Gupta et al. · Nature Medicine · 2020 · 423 citations · Full text

Inflammation, Cancer Immunosurveillance, Reduced Clinical Benefit +12

Integration of eQTL and a Single-Cell Atlas in the Human Eye Identifies Causal Genes for Age-Related Macular Degeneration

Luz D. Orozco, Hsu-Hsin Chen, Christian L. Cox et al. · Cell Reports · 2020 · 221 citations · Full text

Ocular Disease, Genetics, Age-related Macular Degeneration +16

Distinct protein degradation mechanisms mediated by Cul1 and Cul3 controlling Ci stability in <i>Drosophila</i> eye development

Chan-Yen Ou, Yifan Lin, Ying‐Jiun Chen et al. · Genes & Development · 2002 · 184 citations · Full text

CD8+ T cell-intrinsic IL-6 signaling promotes resistance to anti-PD-L1 immunotherapy

Mahrukh Huseni, Lifen Wang, Joanna E. Klementowicz et al. · Cell Reports Medicine · 2023 · 171 citations · Full text

Intratumoral CD103+ CD8+ T cells predict response to PD-L1 blockade

Romain Banchereau, Avantika S. Chitre, Alexis Scherl et al. · Journal for ImmunoTherapy of Cancer · 2021 · 143 citations · Full text