Tomoaki Osugi

Biphasic role for Wnt/β-catenin signaling in cardiac specification in zebrafish and embryonic stem cells

Shuichi Ueno, Gilbert Weidinger, Tomoaki Osugi et al. · Proceedings of the National Academy of Sciences · 2007 · 626 citations · Full text

Life Sciences, Cell Biology, Developmental Biology +17

Signal transducer and activator of transcription 3 in the heart transduces not only a hypertrophic signal but a protective signal against doxorubicin-induced cardiomyopathy

Keita Kunisada, Shinji Negoro, Eiroh Tone et al. · Proceedings of the National Academy of Sciences · 2000 · 274 citations

Life Sciences, Cardiology, Molecular Biology +15

Endogenous Wnt/β-Catenin Signaling Is Required for Cardiac Differentiation in Human Embryonic Stem Cells

Sharon L. Paige, Tomoaki Osugi, Olga K. Afanasiev et al. · PLoS ONE · 2010 · 271 citations · Full text

Life Sciences, Cell Biology, Cell Differentiation +13

Activation of Signal Transducer and Activator of Transcription 3 Protects Cardiomyocytes from Hypoxia/Reoxygenation-Induced Oxidative Stress Through the Upregulation of Manganese Superoxide Dismutase

Shinji Negoro, Keita Kunisada, Yasushi Fujio et al. · Circulation · 2001 · 257 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Signal Transducer and Activator of Transcription 3 Is Required for Glycoprotein 130-mediated Induction of Vascular Endothelial Growth Factor in Cardiac Myocytes

Masanobu Funamoto, Yasushi Fujio, Keita Kunisada et al. · Journal of Biological Chemistry · 2000 · 160 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14