Concepedia

Author

Didier Merciris

Galapagos (France)

Also Known As

D Merciris, D. Merciris, Didier Merciris

24

Publications

276

Citations

8

H-Index

21

Concepts

All Affiliations

Galapagos (France)Hôpital LariboisièreInsermGalapagos (Belgium)Université Paris Cité
DM

About

Didier Merciris is an author at Galapagos (France) specializing in medicine, cell biology, and bone metabolism.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

3

3

102

2

Health Sciences

2

2

59

3

Natural Sciences

1

1

43

4

Biochemistry

1

1

43

5

Biomolecular Engineering

1

1

43

Didier Merciris

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8

Publications

240

Citations

8

H-Index

YearCitations

Heparin‐like dextran derivatives as well as glycosaminoglycans inhibit the enzymatic activity of human cathepsin G

Dominique Ledoux, Didier Merciris, Denis Barritault,

FEBS Letters

2003

43

Discovery of 9-Cyclopropylethynyl-2-((<i>S</i>)-1-[1,4]dioxan-2-ylmethoxy)-6,7-dihydropyrimido[6,1-<i>a</i>]isoquinolin-4-one (GLPG1205), a Unique GPR84 Negative Allosteric Modulator Undergoing Evaluation in a Phase II Clinical Trial

Frédéric Labéguère, Sonia Dupont, Luke J. Alvey,

Journal of Medicinal Chemistry

2020

42

Overexpression of the Transcriptional Factor Runx2 in Osteoblasts Abolishes the Anabolic Effect of Parathyroid Hormone in Vivo

Didier Merciris, Caroline Marty, Corinne Collet,

American Journal Of Pathology

2007

36

Bone loss induced by Runx2 Over‐expression in mice is blunted by osteoblastic over‐expression of TIMP‐1

Corinne Schiltz, Christophe Prouillet, Caroline Marty,

Journal of Cellular Physiology

2009

27

Pharmacological characterization of GLPG1972/S201086, a potent and selective small-molecule inhibitor of ADAMTS5

P. Clément-Lacroix, Christopher B. Little, Margaret M. Smith,

Osteoarthritis and Cartilage

2021

25

Characterization of GLPG0492, a selective androgen receptor modulator, in a mouse model of hindlimb immobilization

Roland Blanqué, L. Lepescheux, Marielle Auberval,

BMC Musculoskeletal Disorders

2014

24

Over-expression of TIMP-1 in osteoblasts increases the anabolic response to PTH

Didier Merciris, Corinne Schiltz, N. Legoupil,

Bone

2006

23

Discovery of Clinical Candidate GLPG3970: A Potent and Selective Dual SIK2/SIK3 Inhibitor for the Treatment of Autoimmune and Inflammatory Diseases

Christophe Peixoto, Agnès Joncour, Taouès Temal-Laib,

Journal of Medicinal Chemistry

2024

20

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