Didier Merciris

Heparin‐like dextran derivatives as well as glycosaminoglycans inhibit the enzymatic activity of human cathepsin G

Dominique Ledoux, Didier Merciris, Denis Barritault et al. · FEBS Letters · 2003 · 43 citations · Full text

Human Cathepsin G, Bioorganic Chemistry, Glycobiology +18

Discovery of 9-Cyclopropylethynyl-2-((<i>S</i>)-1-[1,4]dioxan-2-ylmethoxy)-6,7-dihydropyrimido[6,1-<i>a</i>]isoquinolin-4-one (GLPG1205), a Unique GPR84 Negative Allosteric Modulator Undergoing Evaluation in a Phase II Clinical Trial

Frédéric Labéguère, Sonia Dupont, Luke J. Alvey et al. · Journal of Medicinal Chemistry · 2020 · 42 citations · Full text

Overexpression of the Transcriptional Factor Runx2 in Osteoblasts Abolishes the Anabolic Effect of Parathyroid Hormone in Vivo

Didier Merciris, Caroline Marty, Corinne Collet et al. · American Journal Of Pathology · 2007 · 36 citations · Full text

Sclerostin, Anabolic Effect, Physiology +9

Bone loss induced by Runx2 Over‐expression in mice is blunted by osteoblastic over‐expression of TIMP‐1

Corinne Schiltz, Christophe Prouillet, Caroline Marty et al. · Journal of Cellular Physiology · 2009 · 27 citations

Pharmacological characterization of GLPG1972/S201086, a potent and selective small-molecule inhibitor of ADAMTS5

P. Clément-Lacroix, Christopher B. Little, Margaret M. Smith et al. · Osteoarthritis and Cartilage · 2021 · 25 citations · Full text