Laurent Lecanu

A Neuronal Microtubule-Interacting Agent, NAPVSIPQ, Reduces Tau Pathology and Enhances Cognitive Function in a Mouse Model of Alzheimer’s Disease

Yasuji Matsuoka, Yan Jouroukhin, Audrey Gray et al. · Journal of Pharmacology and Experimental Therapeutics · 2008 · 213 citations

Novel Androstenetriol Interacts with the Mitochondrial Translocator Protein and Controls Steroidogenesis

Andrew Midzak, Nagaraju Akula, Laurent Lecanu et al. · Journal of Biological Chemistry · 2011 · 67 citations · Full text

Beta-Amyloid and Oxidative Stress Jointly Induce Neuronal Death, Amyloid Deposits, Gliosis, and Memory Impairment in the Rat Brain

Laurent Lecanu, Janet Greeson, Vassilios Papadopoulos · Pharmacology · 2005 · 58 citations

Memory Impairment, Abeta42-independent Oxidative Stress, Cell Death +18

Identification of naturally occurring spirostenols preventing β-amyloid-induced neurotoxicity

Laurent Lecanu, Wenguo Yao, Gary Teper et al. · Steroids · 2003 · 49 citations

Medicine, Protein Misfolding, Neuroprotection +2

The spirostenol (22R, 25R)-20α-spirost-5-en-3β-yl hexanoate blocks mitochondrial uptake of Aβ in neuronal cells and prevents Aβ-induced impairment of mitochondrial function

Laurent Tillement, Laurent Lecanu, Wenguo Yao et al. · Steroids · 2006 · 46 citations

Oxysterol, Biochemistry, Mitochondrial Function +9