Chao Shen

METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification

Hengyou Weng, Huilin Huang, Huizhe Wu et al. · Cell stem cell · 2017 · 993 citations · Full text

Hematological Malignancy, Medicine, Mixed-phenotype Acute Leukemia +9

Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion

Rui Su, Lei Dong, Yangchan Li et al. · Cancer Cell · 2020 · 742 citations · Full text

Immune Evasion, Medicine, Stem Cell Mobilization +8

Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally

Huilin Huang, Hengyou Weng, Keren Zhou et al. · Nature · 2019 · 681 citations

Histone Modifications, Chromatin, Transcriptional Regulation +14

RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia

Chao Shen, Yue Sheng, Allen Zhu et al. · Cell stem cell · 2020 · 369 citations · Full text

Systems Biology, Medicine, Acute Myeloid Leukemia +9

R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis

Ying Qing, Lei Dong, Lei Gao et al. · Molecular Cell · 2021 · 332 citations · Full text

Biochemistry, Medicine, Catabolism +8